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RDA’s, ODA’s and Therapeutic
Dose Levels for B-Complex Vitamins

Nutrient

B-1 Thiamin

RDA

1.5 mg

ODA

50 – 100mg

Therapeutic Dose*

3-8 grams

B-2 Riboflavin

1.6mg

25-50mg

300-500mg

B-3 Niacin

20.0mg

500mg

1500mg

B-5 Pantothenic Acid

6.0mg

200-250mg

500-900mg

B-6 Pyrodoxine

2.0mg

50-100mg

300-400mg

B-12 Cobalamine

2.0mcg

500-1000mcg

up to 5,000mcg

Folic Acid

400.0mcg

400-1,000mcg

2-5mg

Biotin

not established

1-3mg

5mg

*When taking therapeutic doses of one B vitamin, the entire B-Complex and adequate magnesium should be taken at a different time during the day to avoid nutritional imbalances and aid in assimilation of the large dose.